Combination of antidepressant & NSAID linked to increased brain bleed risk

Providers treating NMS (neuromusculoskeletal) pain syndromes should pay close attention to patient intake forms relating to prescribed antidepressant use. This is especially true if the provider wishes to advise any NSAID (non-steroidal anti-inflammatory) use. NSAID medications of any kind, including over-the-counter selections, are linked to increasing the risk for brain bleeds when the NSAID is combined with antidepressants. It becomes increasingly important for providers to ask about antidepressant use when considering ANY over-the-counter additions to control NMS pain. For more information, see Medscape article here.